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Dendritics.jpg

Dendritics公司主要关注人类树突状细胞,希望找到能够促使CD34+造血前体细胞转化为树突状细胞(在GM-CSF和TNF-alpha存在的情况下)的细胞因子。在1992-2005年间,大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

 

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

 

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

 

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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Innovative Research of America.jpg

Innovative Research of America(IRA) 是一家致力研发于药物定量定时缓释系统的专业化公司,又称Matrix-Driven Delivery (MDD) 给药系统。该给药系统由一个可生物吸收的基质组成,含有定量可控的活性给药成分,可以以设定的剂量在一定时间范围内进行给药。

 

Since it is not easy to administer drugs and hormones orally to research animals, several delivery methods have been devised as alternatives.  However, most scientists continue to labor with unreliable injectables to conduct their research.

 

Matrix-Driven Delivery (MDD) Pellet(MDD片剂)的优势

Saves time

Ready-to-implant

Insures controlled product release over time

Avoids "peak and valley" effects

Guarantees consistent product preparation

Extends product life against spontaneous breakdown

Extends product life against host-related breakdown

Minimizes experimental variables

Insures safety of the experimenter

Reduces neurophysiological trauma to animal/no excessive handling

Generates more meaningful and reproducible results

Superior to conventional delivery methods

Enhances experimental efficiency

Frees valuable time for creative research

Saves money

 

Innovative Research of America的主要产品包括:

ANTIBIOTICS

ANTI-INFLAMMATORY AGENTS

ANTI-NEOPLASTICS

CATECHOLAMINES & RELATED PRODUCTS

CORTICOIDS & DIURETICS

ESTROGENS & ANTI-ESTROGENS

FATTY ACIDS

MISCELLANEOUS PRODUCTS

NUCLEOTIDE RELATED PRODUCTS

PLACEBO

PROGESTINS

PROSTAGLANDINS

THYROIDS

VITAMINS

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Mediomics.jpg

Mediomics公司2001年成立,致力于为学术机构、制药公司、医学研究者、环境研究者提供创新性的检测试剂盒及生物感应物质。Mediomics拥有Patented Bridge-It® Assay Platform、Patented FRET-PINCER® Assay Platform、Patented TRF-PINCER® Assay Platform三大技术平台。

 

Mediomics, LLC provides innovative assay kits and biosensors needed by academic research laboratories, point of care testing, pharmaceutical companies, as well as medical and environmental research markets.  

 

Technology platforms:

(1)Patented Bridge-It® Assay Platform

Bridge-It® Assays are optimized to measure DNA binding proteins, their ligands, and co-regulators. Mediomics’ Bridge-It® assay was based on a simple idea of splitting the DNA binding site for a protein into two DNA half-sites. The presence of the DNA-binding protein or one of its ligands can be detected by FRET (fluorescence resonance energy transfer).

(2)Patented FRET-PINCER® Assay Platform

FRET-PINCER® Assays are a unique system to quantify the concentration of biomarkers, cells, and pathogens in a broad range of biological samples. The patent-protected FRET-PINCER® Assay system detects the concentration of the target molecule by bringing together complementary single-stranded DNAs and their attached fluorophores to produce fluorescent light through FRET (fluorescence resonance energy transfer).

(3)Patented TRF-PINCER® Assay Platform

TRF-PINCER® Assays are a unique system to quantify the concentration of biomarkers, cells, and pathogens in a broad range of biological samples. The patent-protected TRF-PINCER® Assay platform system detects the concentration of the target molecule by bringing together complementary single-stranded DNAs and their attached fluorophores to produce fluorescent light with Time-Resolved Fluorometry (TRF) sensitivity.

 

主要产品线包括:

(1)Bridge-It® Assay

(2)TR-FRET Bridge-It® Assay

(3)FRET-PINCER® Assay

(4)TR-FRET PINCER®Assay

(5)Other

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Encapsula NanoSciences.jpg

艾美捷科技特约代理Encapsula NanoSciences公司产品。


Encapsula NanoSciences是美国一家致力于提供基于脂质纳米微粒技术(脂质体)的研发和生产的高科技生物纳米技术公司,具有多项知识产权。Encapsula NanoSciences公司现拥有Clodrosome ® , Encapsome ®和Fluoroliposome ® 三个注册商标品牌,提供表面活性脂质体配方和生产服务,包括抗体/多肽交联(Immunosome)、氯磷酸盐脂质体(Clodrosome)及其对照脂质体(Encapsome)、阿霉素脂质体(Doxosome)、DNA和 RNA脂质体 (Genesome)、荧光脂质体(Fluoroliposome)、冻干ATP脂质体(ATPsome)、多款用于人造细胞模型的细胞脂质体(Cellsome)、用于抗肿瘤药物封装的脂质体、多款用于皮肤学及化妆品研发领域的脂质体(Cosmesome) 、以及用于姜黄色素(Curcusome)、肌醇(Inosisome)和宠物专用的营养补充剂脂质体 (Taurosome) 。公司产品服务于学术研究及工业生产等多个领域。通常根据客户需求提供实验室规模的预制脂质体产品。

 

Encapsula NanoSciences is a specialty company focused on providing liposome research, development and manufacturing expertise in the production of lipid-based nanoparticles, also known as liposomes, to clients and partners in both the academic and industrial sectors. Encapsula routinely provides custom laboratory-scale liposome preparations of drug encapsulated liposomes such as Clodrosome® (clodronate liposomes), Encapsome® (plain-control liposomes for clodronate liposomes), Doxosome™ (doxorubicin liposomes), Immunosome™ (reactive liposomes for antibody, protein conjugation), Immunodox™ (reactive liposomes for antibody, protein conjugation containing doxorubicin), Immunogene™ (reactive liposomes for antibody, protein conjugation containing genetic material), Immunofluor™ (reactive liposomes for antibody, protein conjugation containing fluorescent molecules for tracking), Genesome™ (liposomal DNA and RNA), Fluoroliposome™ (fluorescent liposomes), Atpsome™ (ATP liposomes), Cellsome™ (plain liposomes as artificial cell models) and Cosmesome™ (liposomes used in dermatology) to clients in universities and industrial research labs. Encapsula NanoSciences also recently introduced two oral liposomal product lines; NanoLife Nutra for pets and NanoLife Tonics for humans.

 

Encapsula NanoSciences的主要产品包括:

Plain Liposomes as Artificial Cell Models or as Control

Small Molecules Encapsulated into Liposomes

Magnetic Liposomes

Fluorescent Liposomes

Spin labeled Liposomes

Encapsulation of Genetic Materials into the Liposomes

Liposomes used for Electro-Injection

Long-Circulating Sterically Protected Liposomes

Surface Modification of Liposomes

pH Sensitive Liposomes (PSL)

Freeze-Dried Liposomal Systems

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GATTA quant.jpg

GATTA quant有限公司成立于2014年,专注于超高分辨系统中探针的研制,使实验快速、简便、准确。这些探针通过使用特殊的纳米结构,即所谓DNA折纸技术精确定位放置染料分子,可使你测定的显微结果达到几纳米的分辨精度。为确保最优效果和性能,公司会根据您的意愿、要求和意图单独设计定制产品。

 

Gattaquant的主要产品包括:

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       GATTA-BEADS



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       GATTA-BEADS W

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       GATTA-CELLS:

               GATTA-CELLS

               GATTA-CELLS NIR


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         GATTA-SIM NANORULER



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          GATTA-STED NANORULER:     

                      GATTA-STED NANORULER

                      GATTA-STED 3D NANORULER


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        GATTA-CONFOCAL NANORULER



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        Localization Based:

                 GATTA-PAINT HIRES

                 GATTA-PAINT NANORULER

                 GATTA-PAINT 3D – EXPERT AND ULTIMATE LINE

                 GATTA-STORM NANORULER


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        GATTA-AFM:

                GATTA-AFM

                GATTA-AFM 3D NANORULER


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        GATTA-GOLD

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GOLD NANOHELICES (L/R)




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      DNA-PAINT STARTER KIT





GATTAQUANT PRODUCT LEGACY


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艾美捷科技代理Carbon Solutions品牌全系列产品


Carbon Solutions,Inc.(CSI)是一个在碳纳米管技术领域具有显著影响力的品牌,CSI成立于1998年,位于加利福尼亚州里弗赛德。公司自成立之初就明确了其核心目标,即批量生产单壁碳纳米管(SWNT)。CSI因其生产的高质量碳纳米管材料而享有盛誉,已成为领先的纳米技术公司之一。公司能够生产几乎适用于任何应用的碳纳米管,这得益于其对单壁纳米管进行化学处理的能力,从而引入必要的化学官能团,以与常见的工业过程兼容。此外,CSI还是纯度评估技术开发领域的领导者,并制定了碳纳米管工业销售的质量控制和质量保证标准。


CarbonSolutions页面.png


Carbon Solutions产品列表


品名Carbonaceous_PurityMETAL CONTENT规格描述
AP-SWNT60 - 70%< 30 wt% from TGA in air1 gramAs prepared single-wall carbon nanotubes
P2-SWNT> 90%4 - 8 wt. % from TGA in air0.5 gramsPurified, low functionality single-wall carbon nanotubes
P3-SWNT> 90%5 - 7 wt. % from TGA in air0.5 gramsPurified, high functionality single-wall carbon nanotubes
P33-SWNT> 90%4 - 6 wt. % from TGA in air0.1 gramsUltra high purity SWNTs with 1– 3 atomic % carboxylic acid groups, which can be derivatized with a variety of functional groups.
P5-SWNT> 90% (65% ± 15% SWNT loading)4 - 6 wt. % from TGA in air0.1 gramsOrganic soluble, single-wall carbon nanotubes functionalized with ODA
P7-SWNT> 90% (80% ± 10% SWNT loading)4 - 6 wt. % from TGA in air0.1 gramsWater soluble (single-wall carbon nanotubes functionalized with PEG)
P8-SWNT> 90% (35% ± 10% SWNT loading)1 - 3 wt. % from TGA in air0.1 gramsWater soluble (functionalized with PABS)
P9-SWNT> 90%5 - 8 wt. % from TGA in air0.1 gramsAmide functionalized SWNTs
i-SWNT> 45%< 30 wt. % from TGA in air1 gramIndustrial grade electric arc SWNTs synthesized using Ni/Y catalyst
ip-SWNT> 90%> 5 wt. % from TGA in air1 gramIndustrial grade SWNTs purified by air oxidation and subsequently treated to remove the catalyst.  Low functionality and low chemical doping
ipcx-SWNT> 90%> 5 wt. % from TGA in air1 gramIndustrial grade purified SWNTs with carboxylic acid groups
GON/AN/A0.5 gramsGraphene oxide
rGON/AN/A0.5 gramsSynthesized by reduction of GO using sodium borohydride.
NrGO-< 1 wt. % from TGA in air0.5 gramsNitrogen-doped reduced graphene oxide
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